Biochemical and Physiochemical Characteristics of a Pre-B cell Stimulating Factor Produced by the Plasmacytoma cell Line Licr Lon Hmy2
Trudgett, A.; Fay, A.C.; Thompson, J.M.; Mcneill, T.A.
Clinical and Experimental Immunology 59(3): 637-643
1985
ISSN/ISBN: 0009-9104 PMID: 2985306 Document Number: 249519
The pre-B cell colony stimulating activty (pre-B cell CSA) from LICR LON HMY2 conditioned medium (CM) was characterized by a variety of biochemical techniques. Pre-B cell CSA was associated with a heat-stable glycoprotein which has an isoelectric point of 8.3 and a MW as determined by polyacrylamide gel electrophoresis, of 28-32 kilodaltons. The relationship of this activity to previously described factors acting on cells of the B cell lineage is discussed.
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