Monthly changes in the effect of BCG on the migration of polymorphonuclear leucocytes
Bureau, J.P.; Labrecque, G.; Garrelly, L.; Coupé, M.
Research Communications in Chemical Pathology and Pharmacology 49(2): 317-320
1985
ISSN/ISBN: 0034-5164 PMID: 4059656 Document Number: 245785
Monthly changes in the migration of polymorphonuclear leukocytes (PMN) produced by s.c. implantation of BCG-impregnated rayone-made disks were examined over a period of 15 mo. In experiments carried out at 0900 h, the highest PMN count of 40.2 .+-. 8.4 PMN/10,000 .mu.m2 was found in Dec. whereas the lowest count of 14.0 .+-. 4.6 PMN/10,000 .mu.m2 was obtained in April. Mechanisms that could explain the circannual variation are suggested.