Iodine-containing hormones--dipole modifiers of phospholipid membranes

Tsybul'skaia, M.V.; Antonenko, I.N.; Tropsha, A.E.; Iaguzhinskiĭ, L.S.

Biofizika 29(5): 801-805

1984


ISSN/ISBN: 0006-3029
PMID: 6509098
Document Number: 230331
The hormones of thyroid gland thyroxine and triiodothyronine were shown to increase the permeability of bilayer lipid membrane (BLM) and inner mitochondrial membrane for hydrophobic positively charged complex K+-nonactine and to decrease the permeability of these membranes for hydrophobic anion FCCP-. These facts imply that the thyroid hormones affect the phospholipid membranes like the dipole modifyers decreasing the positive potential of hydrophobic region of the membranes in respect to the water phase.

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