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Spin label study of structural changes at different depths of phospholipid membranes after their peroxidation

Panasenko, O.M.; Deev, A.I.; Deeva, I.B.; Azizova, O.A.; Vladimirov, I.A.

Biofizika 30(5): 817-821

1985

ISSN/ISBN: 0006-3029
PMID: 2996625
Document Number: 264755
Changes of structural organization of liposomal phospholipid membranes, after their Fe2+-induced peroxidation were studied at different depth using nitroxyl derivatives of stearic acid. It was established that during Fe2+-induced lipid peroxidation a strong rise in lipid polarity accompanied with immobilization of acyl chains of phospholipids at the depth of 0.6-0.8 nm from the surface was measured. At the same time no significant changes in the structural organization were seen at the depth of 20-22 nm.

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