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Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects

Barletta, C.; Sellini, M.; Bartoli, A.; Bigi, C.; Buzzetti, R.; Giovannini, C.

Bollettino della Societa Italiana di Biologia Sperimentale 60(2): 273-278

1984

ISSN/ISBN: 0037-8771
PMID: 6324828
Document Number: 227518
The influence of vitamin B6 in a dosage of 300 mg X 2 in 24 hrs, on circadian rhythm of plasmatic ACTH, cortisol, prolactin and somatotropin have been studied in 10 normal women. After vitamin B6 24 hrs pattern of ACTH and cortisol is unchanged; prolactin levels are slightly lower, in a statistically unsignificant proportion the night peak of growth hormone is higher in a statistically significant proportion (p. 0.05). The effect of vitamin B6 is likely to me mediated by dopaminergic receptors at hypothalamic level as previous studies by other Authors appear to prove.

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