Serum and pituitary prolactin variations under the influence of pyridoxine and pimozide in the male rat

Oprescu, M.; Dimitriu, V.; Simionescu, L.

Endocrinologie 17(2): 113-117

1979


ISSN/ISBN: 0253-1801
PMID: 462107
Document Number: 145835
Prolactin .+-. SD) by comparison to controls: 33.12 .+-. 11.16 ng/ml, their effect being cumulative (83.75 .+-. 13.86 ng/ml). However, the effect of pyridoxine and pimozide at the central level is different, pyridoxine producing an increase of the pituitary concentration of PRL, while pimozide depleted the stored PRL. Hypothetical mechanisms of pyridoxine action at the pituitary level are discussed.

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