Circadian rhythmicity and cross correlation of plasma gastrin, cortisol and somatostatin levels in ulcerative colitis patients and healthy subjects
Payer, J.; Huorka, M.; Duris, I.; Mikulecký, M.; Kratochvíl'ová, H.; Ondrejka, P.
Hepato-Gastroenterology 40(3): 272-275
1993
ISSN/ISBN: 0172-6390 PMID: 8100796 Document Number: 418064
Gastrin, somatostatin and cortisol circadian (24 hours) rhythmicity was confirmed in healthy subjects. Gastrin and cortisol circadian rhythmicity was studied and also established in patients with ulcerative colitis (UC). UC patients were found to have a lower 24-hour amplitude of plasma cortisol and a shorter acrophase of plasma gastrin. Gastrin correlated positively with somatostatin and negatively with cortisol.
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