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Effect of cycloheximide and actinomycin D on the phospholipid and neutral lipid content of Cunninghamella japonica

Mikhaĭlova, M.V.; Feofilova, E.P.; Rozantsev, E.G.; Arkhipova, G.V.; Shirokova, E.A.

Mikrobiologiia 53(5): 816-821

1984

ISSN/ISBN: 0026-3656
PMID: 6513820
Document Number: 221779
Changes in the composition of neutral lipids and phospholipids were studied during the growth of Cunninghamella japonica under the action of cycloheximide and actinomycin D. The data were used to discuss how the synthesis of enzymes catalysing the formation of individual lipid classes was regulated and whether it would be possible to control the composition of phospholipids and neutral lipids using inhibitors of RNA and protein synthesis. The results are also indicative of a certain correlation between growth phases of the fungus and changes in certain characteristics of membrane lipids.

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