Effect of Eleutherococcys extract on the readaptation processes after 7-hour hypokinesia in rats
Khasina, E.I.; Dardymov, I.V.; Brekhman, I.I.
Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 17(5): 55-58
1983
ISSN/ISBN: 0321-5040 PMID: 6685794 Document Number: 220098
Rats were housed in small cages for 7 days and then were placed into regular cages. The hypokinetic animals lagged behind the controls in their weight gain and reached their normal weight 45 days after the exposure. The hypokinetic exposure stimulated the pituitary-adrenal system, the effect being most pronounced during the first 12 h after the experiment. The hypokinetic effect decreased the glycogen content and the hexokinase and glucose-6-phosphate dehydrogenase activity and increased lactate dehydrogenase and phosphoenol pyruvate carboxykinase activity. The parameters examined returned to normal 45 days after the experiment. The eleuterococcy preparation, the administration of which began immediately after the exposure, expedited the normalization of the parameters almost twofold (by day 20).