Effect of leaf extract from Clerodendron colebrookianum on blood pressure in rats

Gupta, M.; Mazumder, U.K.; Das, S.

Indian Journal of Experimental Biology 32(3): 216-217

1994


ISSN/ISBN: 0019-5189
PMID: 7915249
Document Number: 431112
Hypotensive effect of the extract of leaves of C. colebrookianum was investigated. An extremely bitter fraction was isolated, which gave positive test for alkaloids. The fraction produced fall of blood pressure in a dose dependent manner. The fall of blood pressure was blocked by atropine. Hypertensive effects of adrenaline and noradrenaline were slightly antagonised by the alkaloidal extract.

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