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Modeling a persistent infection by tick-borne encephalitis virus strains in a cell culture of the clawed toad

Izotov, V.K.; Chunikhin, S.P.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 10: 56-59

1982

ISSN/ISBN: 0372-9311
PMID: 7180255
Document Number: 192748
Differences in the ability of 12 tick-borne encephalitis virus strains to induce persistent infection in the culture of clawed frog cells incubated at 26-32 degrees C were shown. In 8 strains the process of persistence was accompanied by the stable preservation of the infectious virus in the culture medium during 10 passages, while in 4 strains the virus disappeared already in passages 3-8.

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