Characteristics of the antitoxic immunity in persons inoculated with chemical typhus vaccine
Nikol'skaia, V.N.; Imamaliev, O.G.; Klimchuk, N.D.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 3: 86-89
1982
ISSN/ISBN: 0372-9311 PMID: 6805180 Document Number: 188716
The determination of toxin-neutralizing antibodies in the sera of persons immunized with chemical typhus vaccine revealed that immunization made both in a single injection and in two injections resulted in the development of antitoxic immunity practically in all vaccinees. No toxin-neutralizing antibodies could be detected 6 months after immunization. The booster injection made at that period resulted in the development of antitoxic immunity which was as pronounced as that developing after primary immunization. In the blood sera of the vaccines the titers of toxin-neutralizing antibodies practically did not differ from those of complement-fixing antibodies.