Interserovar antitoxic immunity to Vibrio cholerae toxins
Belov, L.G.; Adamov, A.K.; Avrorov, V.P.; Kulikova, V.L.; Glian'ko, E.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1988(7): 43-46
1988
ISSN/ISBN: 0372-9311 PMID: 3188734 Document Number: 325407
The immunochemical affinity of V. cholerae enterotoxins, serovars Inaba and Ogawa, has been shown in animal experiments on cross antitoxic immunity in the small intestine, the passive hemagglutination test and the roxin neutralization test. However, antitoxic interaction with both enterotoxins is characteristic only for antibodies to V. cholerae of serovar Inaba, while in animals immune to Ogawa toxin the cholerigenic effect of enterotoxins produced by V. cholerae of both serovars in retained. The possible mechanisms of one-sided cross interserovar antitoxic immunity in cholera are discussed.