Effect of nootropic drugs on the dopamine release and dopamine uptake in structures of the rat striatum
Wustmann, C.; Rudolph, E.; Schwipper, U.; Ranacher, B.; Fischer, H.D.; Schmidt, J.
Acta Biologica et Medica Germanica 41(6): 575-579
1982
ISSN/ISBN: 0001-5318 PMID: 6815946 Document Number: 187256
Nootropics increase the overflow of dopamine from rat striatum slices in a concentration dependent manner, but without relation to their clinical effectiveness. The influence of a nootropic drugs and of amphetamine on the stimulus induced dopamine release points to a relationship between nootropic and nooanaleptic activity, on the one hand, and transmitter release, on the other. Dopamine re-uptake is not altered by nootropics like piracetam.
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