Individual sensitivity to lactose in lactose malabsorption
Gumand-Hoyer, E.; Simony, K.
Ugeskrift for Laeger 137(36): 2064-2068
1975
ISSN/ISBN: 0041-5782 PMID: 1166542 Document Number: 17795
The clinical significance of lactose malabsorption and the individual sensitivity to lactose were investigated in 20 patients with verified lactose malabsorption. Thirteen patients recovered while seven improved only on a lactose-free diet. The healthy patients did not experience following provocation with lactose-free milk but following provocation with increasing quantities of lactose, the tendency to diarrhea and abdominal discomfort increased considerably. Three patients experienced discomfort after provocation with only 5 g lactose. On provocation with increasing quantities of lactose, the seven patients who had not recovered also developed increased abdominal discomfort but none of them developed increased tendency to diarrhea. It is concluded that, in addition to lactose malabsorption, these patients must suffer from irritable colon with tendency to constipation.
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