Model studies of the effect of structural changes in cleaving embryo on electrical parameters of cellular interactions
Dunina-Barkovskaia, A.Ia.; Bozhkova, V.P.; Chaĭlakhian, L.M.
Biofizika 26(6): 1067-1072
1981
ISSN/ISBN: 0006-3029 PMID: 7317491 Document Number: 176386
Two models of the development of the embryo from 1 initial cell by cleavage division are considered. Equivalent electrical schemes were constructed and changes in electrical coupling coefficient (Kec) and input resistance (ri) of the embryos during cleavage were estimated. Considerable influence of cleavage-related changes of membrane parameters on Kec and ri appears at the first 5-10 cleavages and essentially depends on the ratio of contact membrane resistances. A comparison of the estimated curves of Kec and ri with experimental ones (loach and axolotl embryos) showed that the model curves with the ratio rm/rc equaling 100 and 1000, respectively, are very close to the real ones.