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Initiation of anion-selective ionic channels in bilayer membranes at lipid phase transitions

Mol'nar, A.A.; Petrov, V.V.; Predvoditelev, D.A.; Antonov, B.F.

Biofizika 26(3): 538-540

1981

ISSN/ISBN: 0006-3029
PMID: 6266514
Document Number: 173076
A study was carried out to electric parameters of single ionic channels initiated at phase transition of bromidmetilate 1,2-distearoyl-rac-glycero-3-(O-beta-dimethylaminoethyl)-methylphosphonate, whose molecules under conditions given below are possibly charged. It has been shown that changes of transmembrane current appear at phase transition temperature. Comparison between ionic selectivity of channels initiated at Tph.t in the membranes of DSL and its phosphate analog suggests that the channel walls initiated at phospholipid phase transitions are covered with polar groups of molecules.

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