Mammary carcinogenesis in rats fed different amounts and types of fat
Rogers, A.E.; Wetsel, W.C.
Cancer Research 41(9 Pt 2): 3735-3737
1981
ISSN/ISBN: 0008-5472 PMID: 6790168 Document Number: 171813
Rats fed on 20% maize oil or lard showed greater 7,12-dimethylbenanthracene-induced mammary tumorigenesis and slightly greater growth rate than rats fed on 5% fat; 20% maize oil accelerated sexual maturation, but 20% lard did not. In contrast, diets high in beef fat (30%) depressed tumour induction by 7,12-dimethylbenzanthracene or N-fluorenylacetamide compared with a diet containing 15% vegetable oil; dietary lipotrope content had no effect on tumorigenesis.