Further experiments on the pharmacological actions of ergometrine
Mantovani, P.; Santicioli, P.; Di Donato, M.
Bollettino della Societa Italiana di Biologia Sperimentale 57(12): 1346-1351
1981
ISSN/ISBN: 0037-8771 PMID: 6457611 Document Number: 171698
Ergometrine is able to increase the acid output from stomach-perfused rat preparation and its effect is antagonized by cimetidine. The drug excite the H1 receptors of guinea-pig's long strip. On the coronary artery isolated strip the alkaloid causes a potent vasoconstrictor effect mediator through receptors for biogenic amines.
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