DNA polymerase in the microsomal fraction of the myeloblasts of chickens infected with avian myeloblastosis virus
Bartnikowa, W.
Acta Haematologica Polonica 11(4): 229-238
1980
ISSN/ISBN: 0001-5814 PMID: 7293688 Document Number: 157262
Only one DNA polymerase is present in the microsomal fraction of the cells producing AMV. Chromatographically purified enzyme shows the properties of revertase, that is it transcribes in DNA the information encoded in natural RNA. The enzyme possesses identical chromatographic characteristics and the same template specificity as the enzyme isolated from pure AMV virus. Thus the virus enzyme and the cellular DNA polymerase from the microsomal fraction cannot be differentiated on the basis of certain properties.