Effect of lactobacillus and bifidobacteria preparations on the intestinal microflora of mice irradiated with gamma quanta
Korshunov, V.M.; Kissina, E.V.; Ikonnikova, T.B.; Mal'tsev, V.N.; Goncharova, G.I.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 6: 47-54
1980
ISSN/ISBN: 0372-9311 PMID: 7445858 Document Number: 154727
Lactobacilli (strain B12G) and bifidobacteria (strain 75-41), administered orally in a dose of 5 x 10 cells to CBA mice on days 1, 3, 5 and 10 after irradiation with gamma quanta in a dose of 700 rad, restored the "eubiosis" of the intestinal tract, specifically suppressing opportunistic bacteria and facilitating the normalization of the quantitative and qualitative correlation between microbial associations constituting the obligatory intestinal flora. For one thing, the preparations of lactobacilli and bifidobacteria, used for treatment, restored the amount of lactobacilli in the intestinal tract of the irradiated animals to the level, characteristic of the intact animals; for another, these preparations prevented the dissemination of Escherichia, Proteus, Enterococcus in the small intestine and considerably decreased the amount of these microorganisms, as well as Clostridium, in the large intestine.