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Effect of normal and immune IgG, IgM and IgA on the intestinal microflora of mice with experimental dysbacteriosis

Glad'ko, I.A.; Korshunov, V.M.; Pinegin, B.V.; Moshiashvili, I.I.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 10: 60-63

1985

ISSN/ISBN: 0372-9311
PMID: 3911673
Document Number: 253682
Human IgG, IgM and IgA produce a pronounced protective effect, preventing enterobacteria from penetration into the mucous membrane of the proximal section of the small intestine of mice in antibiotic-induced dysbacteriosis. Normal mouse IgG and IgM, in contrast to IgA, are effective against mucosal enterobacteria of the small intestine. Immune mouse IgG, IgM and IgA show greater activity in protecting the mucous membrane than normal immunoglobulins of these classes.

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