On the synthesis of compounds with beta-adrenergic activity
Lehmann, D.; Eckardt, R.; Faust, G.; Fiedler, W.
Die Pharmazie 34(5-6): 278-284
1980
ISSN/ISBN: 0031-7144 PMID: 6106206 Document Number: 154510
It is reported of the synthesis of 1-phenoxy-2-hydroxy-3-aminopropane derivatives with different substituents in the phenoxy residue as well as in the amino group. The potency and the efficacy of these derivatives depend on the substituents. By the introduction of the arylamino-ethyl residue into the nitrogen atom, beta-adrenergic locking agents with marked agonistic activity are obtained.
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