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Effect of neurotropic agents on the healing of experimental mucosal erosions and on the noradrenaline content in the stomach wall

Zabrodin, O.N.; Lebedev, S.N.

Farmakologiia i Toksikologiia 42(5): 484-487

1979

ISSN/ISBN: 0014-8318
PMID: 488317
Document Number: 151851
In immobilized rats with hemorrhagic erosions of gastric mucosa induced by 8-hour electric stimulation, the neurotropic agents were injected intraperitoneally over three days after stimulation was discontinued. Phenamine and melipramine were conductive to healing of the mucous membrane erosions and produced no effect on the recovery of noradrenaline level in the intestinal wall. Clonidin and reserpin inhibited erosion healing and noradrenalline level recovery, whereas eterofen and atropin elicited no effect on the test parameters.

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