Haemorrhagic oedema acute in neonatal skin. Immunological and ultrastructural examination
Lambert, D.; Laurent, R.; Bouilly, D.; Saint-Mont, C.; Estavoyer, J.M.; Agache, P.; Chapuis, J.L.
Annales de Dermatologie et de Venereologie 106(12): 975-987
1979
ISSN/ISBN: 0151-9638 PMID: 533105 Document Number: 145561
There are 3 reports on acute hemorrhagic edema of the skin of infants, an illness which English-speaking authors do not individualize but only regard as a clinical variety of Henoch-Schonlein purpura. The features of the disease described in children < 2 yr of age are very characteristic. A clinical feature is the sudden appearance of edemas on the face and limbs and of cocarde-like purpura with an occasional temperature. A histological feature is the presence of leukocytoclastic vasculitis. The disease is characterized by the deposit of immune complexes. Ultrastructural examination confirms the presence of leukocytoclastic vasculitis accompanied by deposit of immune complexes and of platelets. The nosological aspects of the illness among varieties of allergic vasculitis were studied.