Diesters of 4,4'- (piperazine1,4-diyl) bis-4-oxo 2-butenoic acid
Groszkowski, S.; Najman, L.
Polish Journal of Pharmacology and Pharmacy 31(2): 157-159
1979
ISSN/ISBN: 0301-0244 PMID: 493180 Document Number: 144130
The title compounds were prepared by acylation of piperazine with maleic acid ester chlorides in methylene chloride medium in the presence of K2CO3. In preliminary screening some of them showed marked antimitotic activity on plant materials.
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