Chiral synthesis and enzymatic resolution of (S) - (-) piperazine-2-carboxylic acid using enzyme alcalase
Wu, G.; Zhao, H.; Luo, R.G.; Wei, D.; Malhotra, S.V.
Enantiomer 6(6): 343-345
2001
ISSN/ISBN: 1024-2430 PMID: 11958341 Document Number: 532722
Enantiomerically pure (S)-piperazine-2-carboxylic acid was synthesized by kinetic resolution of methyl-4-(tert-butyroxycarbonyl)-piperazine-2-carboxylate using a low cost enzyme alcalase.
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