The role of the platelets in myocardial infarction induced by isoproterenol in the rat

Cacciapuoti, A.A.; Giuffrida, G.; Mazza, F.; Polverino, W.; Genovese, A.; Cacciapuoti, A.A; Giuffrida, G; Mazza, F; Polverino, W; Genovese, A

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The role of the platelets in myocardial infarction induced by isoproterenol in the rat

Cacciapuoti, A.A.; Giuffrida, G.; Mazza, F.; Polverino, W.; Genovese, A.

Giornale Italiano di Cardiologia 9(7): 767-768

1979

ISSN/ISBN: 0046-5968

PMID: 540709

Document Number: 139403

The AA. suggest that the myocardial infarction induced by isoproterenol in the rat may be determined by phenomenons of intracoronaric platelets aggregation. The effects on the degree and extension of the infarctual necrotic area have been evaluated in a drug with remarkable platelets antiaggregation activity (ASL). The following parameters are considered: wet and dry weight of the organ, and tissutal CPK levels.