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Change in the antiradical activity of surfactant lipids during the development of nonspecific inflammatory processes in rabbit bronchopulmonary tissue

Panevskaia, G.N.; Iarosh, A.M.; Nesterov, E.N.

Voprosy Meditsinskoi Khimii 24(3): 412-415

1978

ISSN/ISBN: 0042-8809
PMID: 580818
Document Number: 137867
Content of total lipids, phospholipids and cholesterol was estimated in surface-active fraction isolated from rabbit lungs. The surface activity and antiradical properties were decreased in the fraction simultaneously with a decrease in phospholipid contents in the course of development of inflammatory process in bronchopulmonary tissue. These data suggested that the antiradical activity, which is essential for protection of the surface-active fraction against free radical peroxidation, was mainly due to the phospholipid component.

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