Effectiveness and mechanism of action of a new plant complex drug in nonspecific inflammatory processes in the bronchopulmonary system
Aleksandrova, A.E.; Makarov, V.G.; Kuznetsov, A.S.; Vishnevetskaia, T.P.; Dmitrieva, O.L.; Kurenkova, T.I.; Makarova, M.N.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 2: 15-17
2003
ISSN/ISBN: 0031-2991 PMID: 12838766 Document Number: 553181
The elixir Bronchofit is an aqueous-alcoholic extract from 7 kinds of plants. It is a balanced compound, rich in biologically active substances including essential oils and flavonoids, possessing a wide spectrum of pharmacological activity. On the model of frog's palate the elixir enhanced the transport function of the ciliated epithelium. On the model "karragenin edema" bronchofit showed a marked anti-inflammatory activity. A noticeable therapeutic effect was registered in rats with induced bronchopulmonary inflammation. Bronchial secretion contained reduced content of glycosaminoglycans while bronchial lavage did of histamine. Also, bronchofit demonstrated a prominent antioxidative activity, an antibacterial action in relation to Str. pyogenes and Bac. cereus. By a total complex of the activities bronchofit is a promising medicine against bronchopulmonary inflammation.