The Role of the Combination of Inflammatory Processes in the Joints and Altered Regional Microcirculation in the Development of Hemophilic Arthropathy
Kosyakova, Y.A.; Kondurtsev, V.A.; Davydkin, I.L.; Zorenko, V.Y.
Klinicheskaia Meditsina 93(4): 52-56
2015
ISSN/ISBN: 0023-2149 PMID: 26155710 Document Number: 681145
To study the role of the combination of inflammatory processes in the joints and altered regional microcirculation as well as factors influencing them in the development of hemophilic arthropathy in 82 patients with recurrent hemarthrosis of the knee and ankle joints by computed IR thermography, laser Doppler flowmetry, and bioimpedancometry for determining fatty and muscle tissue mass. It was shown that deviation of body mass from the normal value were pathogenetically associated with different variants of hemophilic arthropathy. Its risk factors in the patients with continuously recurrent hemarthrosis include epiarticular perfusion, elevated body temperature, low BMI, and muscle mass deficit in excess of 2 kg. 12% of the patients with the history of hemarthrosis-free joints experienced a rise in epiarticular temperature and 6% suffered enhanced perfusion due to latent post-hemorrhagic inflammation.