Subacute alcoholic intoxication in rats: effect of an intravenous injection of glucagon or adrenaline
Thomas, S.; Paulet, G.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 172(1): 84-88
1978
ISSN/ISBN: 0037-9026 PMID: 150907 Document Number: 137360
We have studied the hyperglycemic effect of glucagon (20 microgram/kg) and adrenaline (5 microgram/kg/mn/3 mn) on the rat subjected to a subacute alcoholic intoxication (6,4 g/kg by day during 12 days). The hyperglycemic action of the glucagon is increased while that of the adrenaline slightly decreased. So, the alcoholic intoxication allows to dissociate the both mechanisms of the glycogenolytic action of both hormones. Two hypothesis are brought forward in the discussion.