Baylisascaris procyonis for testing anthelmintics against migratory ascarids
Lindquist, W.D.
American Journal of Veterinary Research 39(11): 1868-1869
1978
ISSN/ISBN: 0002-9645 PMID: 736349 Document Number: 135348
Oral inoculation of mice with 340 embryonated eggs of the nematode, B. procyonis, proved uniformly fatal as early as 13 days after inoculation and as late as 48 days. Mice given 0.5 or 0.25% of pyrantel tartrate in dry feed were protected from cerebral migrations of the worm for 55 days. Treatment with pyrantel pamoate in the feed at the concentration of 0.2% given 7 days before inoculation and 5 days after inoculation also protected mice from migrations throughout the 55-day experiment. Embryonated eggs stored in 0.5% formalin in a 4.degree. C refrigerator for 9 yr were fatal to mice given doses of 340 eggs each.