Antimalarial 6-aminoquinolines. VIII. 2- and 4-amino derivatives
Nickel, P.; Seidel, H.R.; Preissinger, L.; Barnickel, H.; Fink, E.; Dann, O.
Arzneimittel-Forschung 28(4): 578-581
1978
ISSN/ISBN: 0004-4172 PMID: 581931 Document Number: 131147
Ten 2- or 4-amino derivatives of 6-(4-diethylamino-1-methybutylamino)-5,8-dimethoxyquinoline were synthesized and tested in mice infected with Plasmodium vinckei. They were less active than 4-alkoxy derivatives.
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