Muscle irritation caused by different products containing oxytetracycline
Immelman, A.; Botha, W.S.; Grïb, D.
Journal of the South African Veterinary Association 49(2): 103-105
1978
ISSN/ISBN: 1019-9128 PMID: 731653 Document Number: 129616
Muscle irritation was studied in rabbits after use of nine different commercial products. Eight products had propylene glycol and one had polyvinylpyrrolidone as a vehicle. Macroscopic examination 3, 6 and 10 days after intramuscular injection indicated that the irritation caused by the eight products with propylene glycol as a vehicle were very similar. The product with polyvinylpyrrolidone caused much less damage and healing took place more quickly. Saline used as a control caused no tissue damage.