Allergic reactions caused by components of perfume products
Gutman, S.G.; Somov, B.A.
Vestnik Dermatologii i Venerologii 42(1): 62-66
1968
ISSN/ISBN: 0042-4609 PMID: 4244576 Document Number: 4968
By means of skin tests with 50 substances 321 workers of perfumery were examined. Among them 2288 skin tests were made on 97 persons, including 1608 tests on patients with eczemas, dermatites and itching and 680 tests on apparently normal and control persons. By means of the above method increased sensitivity to 18 perfumery and nonperfumery substances was found in 34 persons of whom 26 (including 7 persons with latent allergy) had 42 positive skin tests to 14 perfumery substances. The greatest number of positive skin tests was produced by cinnamic alcohol, cumarin, orange oil, citronellole. The authors suggest that contact with perfumery substances is one of the causes for development of overt and latent allergy in workers of perfumery. This must be taken into consideration in performing prophylactic measures. Most marked allergenic properties are possessed by derivatives of cinnamic acid contained in perfumed bases and compositions of perfumery-cosmetic preparations. A study of allergenic properties of components of perfumery preparations by means of allergologic methods, in particular, by skin tests will be conducive to creation of rational prescriptions of these preparations.
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