Wheat gluten impedes absorption of haloperidol
Freed, W.J.; Luchins, D.J.; Gillin, J.C.; Wyatt, R.J.
Biological Psychiatry 13(6): 769-771
1978
ISSN/ISBN: 0006-3223 PMID: 737265 Document Number: 129382
Pretreatment with wheat gluten resulted in decreased radioactivity in plasma and in brain of mice after oral administration of tritiated haloperidol. Interference by gluten with the rate of haloperidol absorption from the gastrointestinal tract was discussed. Results reported by Singh and Kay, i.e., that wheat gluten had a similar effect in schizophrenic patients, was discussed.
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