Depressed mood impedes pain treatment response in patients with fibromyalgia
Finset, A.; Wigers, S.Hørven.; Götestam, K.Gunnar.
Journal of Rheumatology 31(5): 976-980
2004
ISSN/ISBN: 0315-162X PMID: 15124260 Document Number: 582941
Objective. To investigate prognostic factors in the course of the fibromyalgia syndrome (FM) from baseline to post-treatment. Methods. Fifty-seven patients with FM were examined in a randomized intervention study. Pre-treatment variables were entered into linear regression analyses: gender, age, duration of disease, allocation to treatment, pain distribution (based on a patient-made drawing), fatigue, sleep disturbance, and depressed mood (based on visual analog scores), with pain distribution at treatment completion as the dependent variable. Results. Depressed mood at baseline was a significant predictor of sustained widespread pain at treatment completion. Conclusion. The findings indicate a role for depressed mood as a predictive factor for treatment response.