Unusual giant inclusions in blast cells during acute transformation of chronic myeloid leukemia. Cytochemical and ultrastructural study
Lejeune, F.; Turpin, F.; Lortholary, P.
Pathologie-Biologie 26(1): 7-11
1978
ISSN/ISBN: 0369-8114 PMID: 358097 Document Number: 128512
Unusual giant inclusions are reported in the blast cells during the blastic crisis of a chronic granulocytic leukemia. These inclusions coudl have their origin in degenerated mitochondria, and acid phosphatase positivity suggests fusion with lysosomes. A possible viral etiology is discussed.
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