Ribosome binding to the membranes of Candida albicans
Belousova, I.I.
Biokhimiia 43(3): 473-479
1978
ISSN/ISBN: 0320-9725 PMID: 350291 Document Number: 126673
The in vitro binding of free ribosomes to the membranes of polyenoic antibiotics-sensitive and resistant strains of Candida albicans, considerably differing in the composition of their sterol components, was studied. It was shown that the extent and type of membrane-ribosome interaction is similar in both cases. The dependence of binding on ribosome concentration in the incubation mixture is double-phase, as was shown for different membrane fractions of both sensitive and resistant strains. The role of lipid membrane components, particularly that of sterols in the membrane-ribosome interactions is discussed.