Top Abstract Purchase Related
Home
>
Node
>
Subnode

Diuretic activity of benzimidazole urea derivatives

Pashinskiĭ, V.G.; Romanova, T.V.; Mukhina, N.A.; Shkrabova, L.V.; Tetenchuk, K.P.

Farmakologiia i Toksikologiia 41(2): 196-199

1978

ISSN/ISBN: 0014-8318
PMID: 658365
Document Number: 124738
The chemical structure of benzimidazol urea derivatives and physico-chemical properties of these compounds conditioned by it play a significant role in the manifestation of the emictory effect. Among the study substances a number of compounds displaying a marked, but short-lived diuretic action have been educed. In the manifestation of emictory properties in benzimidazol urea derivatives of importance is the character of the side chain and its ramification and also an even number of carbon atoms in the acyl radical.

Document emailed within 1 workday
Secure & encrypted payments

Alunni Bistocchi, G.; De Meo, G.; Pedini, M.; Ricci, A.; Bastianini, L.; Sposini, T.; Sbaraglia, G.; Jacquignon, P. 1986: New heterocyclic derivatives of benzimidazole with germicidal activity. III. Synthesis and activity of derivatives of (formyl-5'-furyl-2')-2-benzimidazole with different substitutions at position 5 Il Farmaco; Edizione Scientifica 41(12): 970-983
Sánchez-Alonso, R.M.; Raviña, E.; Santana, L.; García-Mera, G.; Sanmartín, M.; Baltar, P. 1989: Piperazine derivatives of benzimidazole as potential anthelmintics. Part 1: Synthesis and activity of methyl-5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates Die Pharmazie 44(9): 606-607
Sawlewicz, J.; Grzybowski, M. 1978: Studies on benzimidazole derivatives. VIII. Reactions of 1-(beta-hydroxy-gamma-choloropropyl)-benzimidazole and its alkyl derivatives with various nucleophilic reagents Acta Poloniae Pharmaceutica 35(3): 273-280
Sorodoc, Y.; Danielescu, G.; Burducea, O.; Cajal, N.; Niclescu-Duvăz, I.; Baracu, I. 1977: Investigations of the antiviral activity of some nitroso-urea derivatives. Inhibitory action of the IOB-252 nitroso-urea derivative on vaccinia virus incell cultures Virologie 28(1): 55-61
Kuźmierkiewicz, W.; Foks, H.; Hać, E.; Strzałkowska-Grad, H. 1985: Synthesis and analgetic and antiinflammatory activity of derivatives of 3-(1H-benzimidazole-2)propanoic acid Die Pharmazie 40(7): 462-464
Pedini, M.; Alunni Bistocchi, G.; Ricci, A.; Bastianini, L.; Lepri, E. 1994: New heterocyclic derivatives of benzimidazole with germicidal activity--XII--Synthesis of N1-glycosyl-2-furyl benzimidazoles Farmaco 49(12): 823-827
Ersan, S.; Nacak, S.; Acar, N.; Noyanalpan, N. 1997: Synthesis and antimicrobial activity of 1-dialkylaminomethyl- 2-(p-substituted phenyl)-5-substituted benzimidazole derivatives Arzneimittel-Forschung 47(4): 410-412
Brzozowski, Z.; Angielski, S.; Jakubowski, Z. 1977: Derivatives of 4-chloro-5-sulfamylbenzoic acid. II. Synthesis and diuretic activity of 5-chloro-2-carboxy-4-sulfamylphenyl hydrazones of various aldehydes and ketones Acta Poloniae Pharmaceutica 34(1): 33-37
Sawlewicz, J.; Wisterowicz, K. 1976: Synthesis of thiocyanates of some benzimidazole derivatives Acta Poloniae Pharmaceutica 33(4): 429-432
Alpan, A.Selcen.; Gunes, H.Semih.; Topcu, Z. 2007: 1H-Benzimidazole derivatives as mammalian DNA topoisomerase I inhibitors Acta Biochimica Polonica 54(3): 561-565
Habib, N.S.; Abdel-Hamid, S.; el-Hawash, M. 1989: Synthesis of benzimidazole derivatives as potential antimicrobial agents Farmaco 44(12): 1225-1232
Zarubina, I.V.; Nurmanbetova, F.N.; Shabanov, P.D. 2005: Experimental justification of the use of benzimidazole derivatives as antiasthenic agents after craniocerebral trauma Eksperimental'naia i Klinicheskaia Farmakologiia 68(3): 46-49
Ying, H.Q.; Dai, X.F. 1993: Studies on chemotherapeutic agents against Schistosomiasis japonica: synthesis of benzimidazole derivatives Yao Xue Xue Bao 28(7): 553-556
Cavier, R.; Notteghem, M.J. 1979: Pharmacological study of tenicidal properties of two anthelmintic benzimidazole derivatives: mebendazole and flubendazole Annales Pharmaceutiques Francaises 37(1-2): 33-36
Naka, T. 1993: Angiotensin Ii receptor antagonist activities and mode of action of benzimidazole-7-carboxylic acid derivatives Nihon Rinsho. Japanese Journal of Clinical Medicine 51(6): 1575-1579
Saczewski, F.; Foks, H.; Sawlewicz, J.; Szulc, K. 1986: Studies of benzimidazole derivatives. XIII. Synthesis of various 2-alpha-hydroxy- and 2-beta-hydroxyalkyl-benzimidazoles Acta Poloniae Pharmaceutica 43(4): 299-307
Zniber, R.; el Hajji, A.J.; Achour, R.; Moussaif, A.; Cherkaoui, M.Z.; el Ghoul, M.; Harrata, A. 1999: Synthesis of benzimidazole derivatives by amino acid action on ortho-phenylenediamine, variously substituted in positions 4 and 5 Therapie 54(5): 637-644
Krotov, A.I.; Kolosova, M.O.; Tret'iakova, S.A.; Cherniaeva, A.I. 1979: Experimental therapy of alveolar hydatid disease. VII. a comparative study on laboratory animals of the effectiveness of a number of benzimidazole derivatives Meditsinskaia Parazitologiia i Parazitarnye Bolezni 48(4): 29-32
Gupta, R.S. 1986: Cross-resistance of nocodazole-resistant mutants of CHO cells toward other microtubule inhibitors: similar mode of action of benzimidazole carbamate derivatives and NSC 181928 and TN-16 Molecular Pharmacology 30(2): 142-148
Monge, A.; Martinez-Merino, V.; Sanmartin, C.; Fernandez, F.J.; Ochoa, M.C.; Bellver, C.; Artigas, P. 1990: Diuretic and hypotensive activities of 4-anilino derivatives of 2-methylthiopyrido[2,3-d]pyrimidines Arzneimittel-Forschung 40(11): 1230-1233