Depletion and disruption of dietary fibre. Effects on satiety, plasma-glucose, and serum-insulin
Haber, G.B.; Heaton, K.W.; Murphy, D.; Burroughs, L.F.
Lancet 2(8040): 679-682
1977
ISSN/ISBN: 0140-6736 PMID: 71495 Document Number: 124162
Ten normal subjects ingested test meals based on apples, each containing 60 g available carbohydrate. Fiber-free juice could be consumed 11 times faster than intact apples and 4 times faster than fiber-disrupted puree. Satiety was assessed numerically. With the rate of ingestion equalized, juice was significantly less satisfying than puree, and puree than apples. Plasma-glucose rose to similar levels after all 3 meals. There was a striking rebound fall after juice, and to a lesser extent after puree, which was not seen after apples. Serum-insulin rose to higher levels after juice and puree than after apples. The removal of fiber from food, and also its physical disruption, could result in faster and easier ingestion, decreased satiety, and disturbed glucose homeostasis which was probably due to inappropriate insulin release. These effects favored overnutrition and, if often repeated, could lead to diabetes mellitus.