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Distribution of exogenous cyclic adenosine 3', 5'-monophosphate in rabbits and cats

Heikkinen, E.R.

Medical Biology 55(2): 82-87

1977

ISSN/ISBN: 0302-2137
PMID: 194115
Document Number: 124142
The appearance and disapperance of total radioactivity in plasma and cerebrospinal fluid (CSF) were studied after a single intravenous injection of tritium-labelled cyclic adenosine 3', 5'-monophosphate (cAMP) into rabbits and cats. The radioactivity was rapidly cleared both from plasma and relatively stable when compared to plasma cAMP level. Exogenous cAMP in plasma does not seen to distribute into CSF by a simple diffusion.

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