GABA and diseases of the extrapyramidal system
Carrieri, P.
Acta Neurologica 32(5): 697-704
1977
ISSN/ISBN: 0001-6276 PMID: 22223 Document Number: 118925
Metabolism of GABA, the major inhibitory neurotransmitter in the nervous system, and its enzyme glutamine decarboxylase (GAD) action; GABA and GAD concentrations in the basal ganglia and correlations between GABA and other neurotransmitters were evaluated. Starting from GABA and GAD decreasing in the basal ganglia, some pathogenetic remarks on Parkinson's disease and Huntington's chorea are emphasized.