Effect of dibenzepin hydrochloride on the oxygen, glucose uptake and oxidative phosphorylation of rat brain in vitro
Velasco-Martín, A.; Pérez Bejarano, R.; González de Zárate, J.L.; Saiz-Martínez-Acitores, I.; Moreno González, A.
Il Farmaco; Edizione Scientifica 32(9): 672-677
1977
ISSN/ISBN: 0430-0920 PMID: 20331 Document Number: 118906
Dibenzepin hydrochloride (10(-3) M) decreases the oxygen uptake of whole brain homogenates and uncouples brain mitochondrial oxidative phosphorylation. At the same concentration this drug inhibits oxygen uptake of rat brain slices when calcium is absent in the incubation or then contains an excess of potassium.
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