Effect of intra-arterial infusion of papaverine hydrochloride on brain tissue oxygen pressure in the management of severe vasospasm following aneurysmal subarachnoid hemorrhage
Reisch, R.; Filippi, R.; Böcher-Schwarz, H.; Mauer, D.; Ringel, K.; Stoeter, P.; Perneczky, A.
Acta Neurochirurgica. Supplement 77: 191-193
2001
ISSN/ISBN: 0065-1419 PMID: 11563284 Document Number: 538202
Despite considerable advances in diagnostic, surgical and interventional techniques, the overall outcome for patients with aneurysmal subarachnoid hemorrhage remains poor. Concerning perioperative course, cerebral ischaemia is one of the major factors causing secondary brain demage. The aim of all therapeutic interventions is the stabilization and maintance of cerebral blood flow and tissue oxygenation in order to prevent cerebral ischaemia and consecutively brain infarction [1.