B-A transition of DNA in aqueous solutions of nonelectrolytes
Malenkov, G.G.; Minasian, K.A.
Molekuliarnaia Biologiia 11(2): 352-360
1977
ISSN/ISBN: 0026-8984 PMID: 752781 Document Number: 118390
Circular dichroism spectra of DNA in ternary water-nonelectrolyte solutions (water--ethanol--isopropanol and water--ethanol--dioxane) show that the decrease in water content at various nonelectrolyte ratios leads to the transition of DNA from B- to A-form. Water activity values in B-A transition region were calculated. The transition takes place within the range of water activity and DNA conformations have been plotted on triangular diagrams.