Antigenic characterization of Echinococcus granulosus cysts
Varela-Diaz, V.M.; Torres, J.M.
Bollettino dell'Istituto Sieroterapico Milanese 56(4): 302-309
1977
ISSN/ISBN: 0021-2547 PMID: 71902 Document Number: 116698
Limited numbers of antigens were detected in the structura; components of Echinococcus granulosus cysts by double diffusion and immunoelectrophoresis tests using homologous and heterologous antisera without antibody activity to host serum contaminants. Although antigens common to the germinal membranes, laminated layers and protoscoleces were demonstrated, no evidence was found of antigen-sharing between the laminated layer and hydatid fluid from fertile and sterile cysts. These fluids, however, had antigenic determinants in common with protoscoleces. Antigens responsible for the formation of a characteristic cathodic arc were detected but only in the 3 structural cyst components. In contrast, E. granulosus arc 5 antigens were found solely in hydatid fluid. These observations suggest that these 2 antigen groups are of somatic and metabolic origin, respectively. [AS].