A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA
Maddison, S.E.; Slemenda, S.B.; Schantz, P.M.; Fried, J.A.; Wilson, M.; Tsang, V.C.
American Journal of Tropical Medicine and Hygiene 40(4): 377-383
1989
ISSN/ISBN: 0002-9637 PMID: 2712196 Document Number: 340882
An echinococcus antigen with an apparent molecular weight of 8 kDa was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. Specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.