Parenteral administration of sorbitol solution and its impact on sorbitol, glucose, fructose and lactate concentration in the blood of cattle, sheep and piglets
Brenner, K.V.; Kolb, F.E.
Archiv für Experimentelle Veterinarmedizin 30(1): 109-119
1976
ISSN/ISBN: 0003-9055 PMID: 962477 Document Number: 106412
Significant rise of fructose in the blood plasma of cattle resulted from an application of sorbite solution (0.5 g sorbite per kg live weight), with its onset as early as during the infusion. The highest concentration was reached 15 minutes after completion of infusion. Rise in glucose (11 mg/100 ml plasma on average) failed to prove statistically significant and dropped temporarily (after 60 to 120 minutes) below the original value. The lactate level in the blood went up temporarily and reached its maximum 30 minutes from the end of infusion. Sorbite solution (1 g/kg live weight) was intravenously applied to sheep and tock fructose to its maximum after 30 minutes. Intraperitoneal application of sorbite solution (1 g/kg live weight) was tolerated well also by piglets and triggered an age-dependent decline of glucose in blood plasma.